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Encephalitozoon intestinalis : ウィキペディア英語版
Encephalitozoon intestinalis

''Encephalitozoon intestinalis'' is a parasite.〔 It can cause microsporidiosis.〔
It is notable as having one of the smallest genome among known eukaryotic organisms, containing only 2.25 million base pairs.〔 Its genome was completely sequenced in 2010.〔
''E. intestinalis'' originally named Septata intestinalis, was reclassified based on morphologic, antigenic
and molecular similarities with other species of the genus Encephalitozoon. Recently, Some domestic
and wild animals have been found to be naturally infected with ''E. intestinalis'' and some other
microsporidian species.〔Centers for Disease Control and Prevention. 2013.〕
''E. intestinalis'' is transmitted in contaminated water. It causes Gastro-Intestinal tract infection which
subsequently leads to diarrhea and circulates to the ocular, genitourinary and respiratory tracts.
Research has proven that ''E. intestinalis'' infection can increase host cell nuclear mutation rate.〔
== Disease ==
''Microsporidia'' are obligate intracellular opportunistic fungi that cause significant pathology in
immunocompromised (simply put: having an impaired immune system) hosts. Like other
obligate intracellular pathogens, ''microsporidia'' exert significant stress on infected host cells.
''Microsporidia'' infection alters host cell cycle regulation and can lead to development of
multinucleated host cells.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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